Mast cell tumors (mastocytomas) in dogs are graded according to their location in the skin, their presence of inflammation and how well they are differentiated.
- Grade 1 cells - well differentiated with low potential for metastasis.
- Grade 2 cells - intermediately differentiated with potential for locally invasive metastasis.
- Grade 3 cells - poorly differentiated or undifferentiated with high potential for metastasis.
- Stage 1 - single tumor, no metastasis.
- Stage 2 - single tumor with metastasis into the surrounding lymph nodes.
- Stage 3 - multiple skin tumors, or a large tumor that has invaded subcutaneously.
- Stage 4 - presence of a tumor, with metastasis to an organ or widespread mast cell presence in blood.
|Canine Mast Cell Tumor with Toluidine Blue Staining (C) Lumenera|
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